Detection of Ultrasound Contrast Signals in the Cerebral Circulation During Stress Echocardiography
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Detect abnormalities in cerebral blood flow
研究概览
简要总结
To Determine whether transcranial ultrasound can detect the presence of intravenously injected microbubbles used routinely for dobutamine stress echocardiography.
详细描述
The purpose of this study is to determine whether the intravenous microbubbles used to improve border delineation during dobutamine stress echocardiographies (DSE) can be detected within the cerebral circulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •male or female age >19 years of age
- •scheduled for a stress echocardiogram
- •negative urine pregnancy test within two hours of ultrasound contrast administration required for females of childbearing age unless post-menopausal or with evidence of surgical sterilization
- •be conscious and coherent, and able to communicate effectively with trial personnel
排除标准
- •pregnant or lactation
- •life expectancy of less than 2 months or terminally ill
- •Known or suspected hypersensitivity to ultrasound contrast agent used for the study
- •complicated hemodynamic instability
- •Known left main disease
结局指标
主要结局
Detect abnormalities in cerebral blood flow
时间窗: immediate
All Patients undergoing dobutamine stress echocardiography have an intravenous line placed and a continuous infusion of a commercially available contrast agent administered. Prior to contrast infusion, baseline transcranial ultrasound images at 0.4 mechanical index using low mechanical index pulses and color Doppler will be performed and recorded. After this the contrast infusion will begin, and resting cardiac images will occur.
次要结局
- if cerebral vascular disease is detected it would lead to further testing that may better identify abnormalities.(within 30 minutes)