Ultrasound Assessment of Changes in the Diameter of the Common Carotid Artery After Increasing the Preload of the Heart With Passive Leg Raise and Intravenous Fluid Infusion
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Critical Illness
- Sponsor
- Uniwersytecki Szpital Kliniczny w Opolu
- Locations
- 1
- Primary Endpoint
- Changes in the diameter of the common carotid artery
- Status
- Withdrawn
- Last Updated
- 6 years ago
Overview
Brief Summary
Passive leg raise (PLR) and fluid challenge are useful tools in assessing the fluid responsiveness. However, they require continuous monitoring of cardiac output, which is usually an invasive technique and in some cases not always available. Vascular ultrasound can be an alternative to cardiac output monitoring in a fluid status evaluation. The common carotid artery (CCA) is an easily accessible vessel. It has recently been noted that the diameter of this artery changes after an intravenous fluid bolus. It is possible that the change in the diameter of the common carotid artery during passive leg raise and fluid challenge can be a predictor of fluid responsiveness.
Investigators
Maciej Piwoda
Principal Investigator
Uniwersytecki Szpital Kliniczny w Opolu
Eligibility Criteria
Inclusion Criteria
- •mechanically ventilated patients with circulatory failure, who are monitored with PiCCO and need fluid responsiveness assessment
Exclusion Criteria
- •contraindication for the volume administration (hydrostatic pulmonary edema or other evidence of fluid overload)
- •contraindication for PLR test (e.g. after trauma)
- •lack of possibility to examine the carotid arteries
- •bilateral carotid surgery in the past
- •bilateral anatomical defects of the carotid arteries
- •unstable cardiac rhythm (e.g. atrial fibrillation)
Outcomes
Primary Outcomes
Changes in the diameter of the common carotid artery
Time Frame: 1 minute after PLR test and 1 minute after fluid challenge
The diameter will be measured with ultrasound
Secondary Outcomes
- Evaluation the value of changes in the diameter of CCA as the predictor of fluid responsiveness.(1 minute after PLR test and 1 minute after fluid challenge)