Ultrasound Assessment of Changes in the Diameter of the Common Carotid Artery After Increasing the Preload of the Heart With Passive Leg Raise and Intravenous Fluid Infusion
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Changes in the diameter of the common carotid artery
研究概览
简要总结
Passive leg raise (PLR) and fluid challenge are useful tools in assessing the fluid responsiveness. However, they require continuous monitoring of cardiac output, which is usually an invasive technique and in some cases not always available. Vascular ultrasound can be an alternative to cardiac output monitoring in a fluid status evaluation. The common carotid artery (CCA) is an easily accessible vessel. It has recently been noted that the diameter of this artery changes after an intravenous fluid bolus. It is possible that the change in the diameter of the common carotid artery during passive leg raise and fluid challenge can be a predictor of fluid responsiveness.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •mechanically ventilated patients with circulatory failure, who are monitored with PiCCO and need fluid responsiveness assessment
排除标准
- •contraindication for the volume administration (hydrostatic pulmonary edema or other evidence of fluid overload)
- •contraindication for PLR test (e.g. after trauma)
- •lack of possibility to examine the carotid arteries
- •bilateral carotid surgery in the past
- •bilateral anatomical defects of the carotid arteries
- •unstable cardiac rhythm (e.g. atrial fibrillation)
结局指标
主要结局
Changes in the diameter of the common carotid artery
时间窗: 1 minute after PLR test and 1 minute after fluid challenge
The diameter will be measured with ultrasound
次要结局
- Evaluation the value of changes in the diameter of CCA as the predictor of fluid responsiveness.(1 minute after PLR test and 1 minute after fluid challenge)
研究者
Maciej Piwoda
Principal Investigator
Uniwersytecki Szpital Kliniczny w Opolu