Hydrogen-rich Water and Treatment of Mucositis Caused by Radiation Therapy in Head and Neck Cancer Patients

Early Phase 1

Completed

• Conditions: Mucositis Oral
• Interventions: Dietary Supplement: Control; Dietary Supplement: Hydrogen tablets

• Registration Number: NCT05278260
• Lead Sponsor: Stony Brook University

Brief Summary

This study explores the effects of hydrogen-rich water on alleviating the radiation-induced acute mucositis in head and neck cancer patients

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-03-03
• Study First Submitted QC: 2022-03-03
• Study First Posted: 2022-03-14
• Study Start: 2022-05-25
• Primary Completion: 2024-11-13
• Study Completion: 2024-11-13
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-12
• Last Update Posted: 2025-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Diagnosis of a biopsy proven head and neck cancer, early or advanced stage, primary or recurrent tumor,
• Planning to receive daily fractionated radiotherapy for over 4 weeks' duration
• Karnofsky Performance Score (KPS) of at least 70
• Able to describe pain
• Able to swallow food and water
• Able to sign consent

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Control	-
Active	Hydrogen tablets	-

Primary Outcome Measures

Name	Time	Method
Number of participants who develop grade 3 oropharyngeal mucositis	3 months after completing radiation therapy

Trial Locations

Locations (1)

Stony Brook Cancer Center; 🇺🇸 Stony Brook, New York, United States