JPRN-UMIN000004487
Completed
Phase 2
Phase II Trial of Preoperative Chemotherapy and Bevacizumab in Patients With Stage IIIA Non-Squamous Non-Small Cell Lung Cancer - Phase II Trial of Preoperative Chemotherapy and Bevacizumab
Conditionson-squamous, Non-small cell lung cancer
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- on-squamous, Non-small cell lung cancer
- Sponsor
- Osaka International Cancer Institute
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\)Active double cancer 2\)Current history of hemoptysis 3\)Evidence of bleeding diathesis or coagulopathy 4\)With great vessel invasion 5\)Cavity in tumor 6\)History of uncontrollable pericardial effusion 7\)History of severe heart disease 8\)Current or previous history (within the last 1 year) of symptomatic cerebrovascular disease 9\)Active infectious disease in need of intravenous administration of anti\-bacterial, anti\-fungal, or anti\-viral drugs 10\)Receiving anticoagulant drug (except Aspirin within 324 mg/day) 11\)Uncontrollable Gastrointestinal ulceration 12\)Current or previous(within the last 1 year)history of GI perforation 13\)Uncontrollable systemic disease (hyper tension or diabetes mellitus) 14\)Interstitial pneumonia or pulmonary fibrosis detectable on chest Xp 15\)Peripheral neuropathy \> Grade2 16\)With a history of drug sensitivity 17\)History of pregnancy or lactation 18\)No intention to practice birth control 19\)Patients whose participation in the trial is judged to be inappropriate by the attending doctor
Outcomes
Primary Outcomes
Not specified
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