Addictive Potential of Little Cigars/Cigarillos in Dual Users: Effect by Flavor and Gender
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Demand Elasticity
研究概览
简要总结
This study is about whether or not little cigars and cigarillos cause or maintain addiction, and if flavors, such as fruit, make them more addictive. The purpose of this study is to understand the addiction potential of little cigars and cigarillos compared to cigarettes in young adults who smoke both products. This study will also look at the differences between men and women. In the rest of this form, little cigars or cigarillos will be referred to as LCCs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 34 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Current regular dual user of little cigars/cigarillos (LCCs) and cigarettes, defined as: (a) report smoking cigarettes on ≥ 8 of the past 30 days, and (b) report smoking unaltered LCCs (without marijuana) on ≥ 8 of the past 30 days.
- •Able to speak, read and understand English
- •Age 18-34 years of age
- •Stable residence (not planning to move during study period)
- •Not intending to quit smoking cigarettes or LCCs within the next 2 weeks
- •An expired carbon monoxide (CO) level of at least 4 ppm of expired air to verify smoking status
排除标准
- •Pregnant for women (verified by urine pregnancy test at Visits 1 and 2)
- •Current use of (or plans to use in the next 2-3 weeks) nicotine replacement products or cessation products (e.g., bupropion) to minimize confounding effects of another product)
- •Positive breath alcohol screen (breath alcohol level (BAL) > 0 g/ml; one re-test allowed; assessed at Visits 1, 2, and 3)
- •Illicit drug use other than marijuana (verified by positive drug toxicology test at Visits 1 and 3; one re-test allowed)
- •Met criteria for Cannabis Dependence assessed by the Cannabis Use Disorders Identification Test-Revised (CUDIT-R)
研究组 & 干预措施
Flavored LCCs
Half of the group will start with a flavored little cigar/cigarillo (LCC) and cross over to unflavored LCC. The LCCs will be a popular brand already available for sale on the market.
干预措施: Flavored and unflavored little cigars/cigarillos (LCCs) (Other)
Unflavored LCCs
Half of the group will start with an unflavored little cigar/cigarillo (LCC) and cross over to flavored LCC. The LCCs will be a popular brand already available for sale on the market.
干预措施: Flavored and unflavored little cigars/cigarillos (LCCs) (Other)
结局指标
主要结局
Demand Elasticity
时间窗: Post-treatment (after being assigned to use it for 7 days)
Hypothetical consumption of LCCs as prices increase. These are the model-adjusted predicted mean values of elasticity, adjusted for covariates. It is the expected change in consumption for a one unit change in price.
Demand Intensity
时间窗: Post-treatment (after 7 days of being assigned to condition)
Hypothetical consumption when free. These are the model-adjusted predicted mean values of intensity, adjusted for covariates.
次要结局
未报告次要终点
研究者
Erin Mead-Morse
Assistant Professor
UConn Health