Tranexamic Acid in Hip Fracture Surgery
Completed
- Conditions
- Hip Fracture
- Registration Number
- NCT02736383
- Lead Sponsor
- Spectrum Health Hospitals
- Brief Summary
To determine if TXA utilization is effective at reducing transfusion rates in elderly patients undergoing surgery for treatment of a hip fractures.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 142
Inclusion Criteria
- Acute, isolated, unilateral femoral neck, intertrochanteric, and per trochanteric hip fractures confirmed by anteroposterior/lateral hip radiographs, computed tomography, or magnetic resonance imaging.
- Age 65 and older
- Low energy mechanism of injury
- Hip fracture fixation performed within 48 hours
- English speaking
- Anticipated medical optimization for operative fixation
- No other major trauma
Exclusion Criteria
- Retained hardware around the affected hip
- Infection around the affected hip
- Transfer patients with a length of stay > 24 hours at the transferring hospital
- Diagnosis of deficient natural anticoagulation
- Known congenital thrombophilia (Deficiency of Protein C, S, Antithrombin)
- Known allergy to TXA
- Patients undergoing percutaneous pinning of the hip fracture
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood Transfusion Rate 6 weeks Blood transfusion rates during the patients hospital stay will be assessed.
- Secondary Outcome Measures
Name Time Method Hospital Length of stay 6 weeks The patients length of stay in the hospital will be determined.
Post operative complications 6 weeks Post operative complications will be assessed through the 6 weeks.
Hospitalization costs 6 weeks Economic evaluation for inpatient and re-admission will be assessed.