NCT02736383已完成不适用
Effectiveness of Tranexamic Acid (TXA) in Reducing Blood Loss in Hip Fracture Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 142
- 主要终点
- Blood Transfusion Rate
研究概览
简要总结
To determine if TXA utilization is effective at reducing transfusion rates in elderly patients undergoing surgery for treatment of a hip fractures.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute, isolated, unilateral femoral neck, intertrochanteric, and per trochanteric hip fractures confirmed by anteroposterior/lateral hip radiographs, computed tomography, or magnetic resonance imaging.
- •Age 65 and older
- •Low energy mechanism of injury
- •Hip fracture fixation performed within 48 hours
- •English speaking
- •Anticipated medical optimization for operative fixation
- •No other major trauma
排除标准
- •Retained hardware around the affected hip
- •Infection around the affected hip
- •Transfer patients with a length of stay > 24 hours at the transferring hospital
- •Diagnosis of deficient natural anticoagulation
- •Known congenital thrombophilia (Deficiency of Protein C, S, Antithrombin)
- •Known allergy to TXA
- •Patients undergoing percutaneous pinning of the hip fracture
结局指标
主要结局
Blood Transfusion Rate
时间窗: 6 weeks
Blood transfusion rates during the patients hospital stay will be assessed.
次要结局
- Hospital Length of stay(6 weeks)
- Post operative complications(6 weeks)
- Hospitalization costs(6 weeks)
研究者
相似试验
已完成
4 期
Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma SurgeryTranexamic AcidTraumaLower Extremity FractureNCT04986813Jaspreet Singh100
撤回
4 期
The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip FracturesBlood LossHip FractureNCT01940536Hospital for Special Surgery, New York
Unknown
3 期
Use of Transexamic Acid in Hip ReplacementBleedingTransfusion Related ComplicationNCT02587845Samsung Medical Center150
Unknown
2 期
Study of Tranexamic Acid for Reducing Blood Requirement in Patients Undergoing Major Gastro-intestinal SurgeryHepatocellular CancerPancreatic CancerGastric CancerColon CancerNCT01655641Tribhuvan University Teaching Hospital, Institute Of Medicine.118
已完成
不适用
The Safety of Intravenous Tranexamic Acid in Patients Undergoing Supratentorial Meningiomas ResectionSeizuresMeningiomaNCT04595786Beijing Tiantan Hospital228