IRCT20100127003210N25尚未招募2 期
Comparison of apixaban and dalteparin in thromboprophylaxis for hematopoietic stem cells transplant recipients
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Patients aged = 18 years, candidates for bone marrow stem cell transplantation
- •Weight = 40 kg
- •Khorona score = 2 or caprini score = 5
- •Life expectancy longer than 60 days and performance status score = 2 according to ECOG criteria
- •Creatinine clearance = 30 mL / min
- •Platelet count = 50000 / µL
- •Liver function test (AST, ALT) below three times the upper limit normal
- •INR = 1.6
- •No pregnancy
排除标准
- •Bacterial endocarditis
- •Active bleeding, uncontrolled hypertension (SBP> 170, DBP> 110)
- •Patients receiving haploidentical allogenic transplantation consuming cyclophosphamide
- •Active bleeding in seven days or more before randomization
- •Severe liver disease (known as Childs Pugh cirrhosis class B or C) or kidney disease (creatinine clearance less than 30 ml / min)
- •Known anticoagulation disorder
- •Thrombocytopenia due to previous heparin use
研究者
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