COMPARISON OF ANALGESIC EFFICACY OF LOCAL WOUND INFILTRATION WITH LEVOBUPIVACAINE PLUS DEXMEDETOMIDINE AND ROPIVACAINE PLUS DEXMEDETOMIDINE IN LOWER ABDOMINAL SURGERIES: A RANDOMISED CONTROLLED TRIAL
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- To Compare the efficacy of post operative analgesia of two drugs at 30mins,4hrs,8hrs,12hrs,20hrs,
Study Overview
Brief Summary
To compare the better analgesic efficacy of infiltration of the two drugs with additives i.e., levobupivacaine with dexmedetomidine and ropivacaine with dexmedetomidine for postoperative pain relief in patients undergoing lower abdominal surgeries
Levobupivacaine with dexmedetomidine and ropivacaine with dexmedetomidine were the two drugs with adjuvants used for better post operative pain relief and reduce the frequency of rescue analgesia.
Purpose of this study to get better post operative pain relief and reduce the frequency of rescue analgesia and it is cost effective also.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients with ASA classification I & II Age of 18 to 60yrs Posted for elective lower abdominal surgeries Surgical duration of 1hr to 2hrs.
Exclusion Criteria
- •Patient Refusal Allergic to local anaesthetics Failed Sub Arachnoid Block getting converted to GA Patchy Sub Arachnoid Block Obese Individual Lower Segment Caesarean Section.
Outcomes
Primary Outcomes
To Compare the efficacy of post operative analgesia of two drugs at 30mins,4hrs,8hrs,12hrs,20hrs,
Time Frame: To Compare the efficacy of post operative analgesia of two drugs at 30mins,4hrs,8hrs,12hrs,20hrs, | 24hrs and their analgesic duration
24hrs and their analgesic duration
Time Frame: To Compare the efficacy of post operative analgesia of two drugs at 30mins,4hrs,8hrs,12hrs,20hrs, | 24hrs and their analgesic duration
Secondary Outcomes
- Frequency of rescue analgesia whenever VAS score more than or equal to 4 in first 24hrs(4hrs,8hrs,12hrs,20hrs,)
Investigators
Dr G Vignesh
Karpaga Vinayaga Institute Of Medical Sciences and Research Centre