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Economic evaluation of treatment modalities for position dependent obstructive sleep apnea patients<br>

Completed
Conditions
Obstructive sleep apnea sydrome (OSAS)
sleep-disordered breathing (SDB)
10046304
Registration Number
NL-OMON44815
Lead Sponsor
Onze Lieve Vrouwe Gasthuis
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
130
Inclusion Criteria

- Diagnosis with symptomatic mild or moderate OSA (15 < AHI < 30).
- Diagnosis of 10 to 90% supine position during the night.
- AHI supine is 2 > as high as AHI non-supine.

Exclusion Criteria

- Many dental problems; insufficient teeth for wearing MRA
- Medication used/ related to sleeping disorders
- Central Sleep Apnea Syndrome.
- Night or shifting work.
- Severe chronic heart failure,
- Medical history of known causes of tiredness by day or severe sleep disruption (insomnia, PLMS, Narcolepsy).
- Seizure disorder.
- Known medical history of mental retardation, memory disorders or psychiatric disorders.
- Shoulder, neck and back complaints.
- Reversible morphological upper airway abnormalities (e.g. enlarged tonsils),
- Inability to provide informed consent.
- Simultaneous use of other treatment modalities to treat OSA.
- Previous treatment for OSA with MRA, CPAP or SPT
- Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>primary ouctome: AHI </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>1) Outcome of Quality of Life questionnaires; EQ-5D, ESS and FOSQ.<br /><br>2) (Societal) costs of treatment; Healthcare Consumption, Illness and Work<br /><br>(HCIW) questionnaire (PCQ/MCQ, successors of TiC-P and PRODISQ).<br /><br>3) Compliance, i.e. more than 4 hours of usage per night.<br /><br>4) Cardiovascular parameters: blood pressure, pulse rate, BMI and neck<br /><br>circumference</p><br>
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