Mechanisms of action of selective serotonin reuptake inhibitor (SSRI) pharmacotherapy for social anxiety disorder: a randomised neuroimaging trial

ppsala University (Sweden)0 个研究点目标入组 48 人开始时间: 2014年3月17日最近更新: 2017年11月20日

适应症

试验速览

暂无简介。

•1. Social anxiety disorder (social phobia), according to DSM-5, must be the main diagnosis as assessed with the structured clinical interview for DSM disorders (SCID)
•2. Otherwise somatically healthy
•3. Age 18-65, but not postmenopausal
•4. Willingness to participate in a symptom provocation brain imaging trial

•1. Treatment of social anxiety within the three months preceding the study
•2. Current serious or dominant psychiatric disorder other than social anxiety disorder (e.g. psychosis, major depressive disorder, bipolar disorder)
•3. Suicidal ideation
•4. Chronic use of prescribed medication that could influence the results (e.g. other anxiolytic or antidepressant drugs, certain hypnotics or herbs like St John?s Wort)
•5. Abuse of alcohol or narcotics
•6. Pregnancy or planned pregnancy during the study period
•7. Menopause
•8. Previous positron emission tomography (PET) examination
•9. Contraindications for MRI investigation (e.g. implants or other metal objects in the body, brain and heart operations)

发起方

ppsala University (Sweden)