NCT01028443已完成4 期
Efficacy of Topical Cyclosporine A for Treatment and Prevention of Graft Rejection in Corneal Grafts With Previous Rejection Episodes
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 试验地点
- 1
- 主要终点
- The rate of rejection after drop sessation
研究概览
简要总结
The use of topical Cyclosporine A early after an episode of endothelial graft rejection after penetrating keratoplasty and continuing its administration for 6 months can reduce the course of that episode and recurrence of the rejection.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Penetrating keratoplasty in eyes without vascularization
排除标准
- •History of previous intraocular surgery
研究组 & 干预措施
Cyclosporine A 2%
Active Comparator
干预措施: Sandimmune (Drug)
Artificial tears
Placebo Comparator
干预措施: Artelose (Drug)
结局指标
主要结局
The rate of rejection after drop sessation
时间窗: 3 years
次要结局
未报告次要终点
研究者
研究点 (1)
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