ACTRN12618000102279Completed未知
Does probiotic treatment affect gut dysbiosis and cognitive outcomes in people with Huntington's Disease?
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Monash University
- Enrollment
- 84
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Randomised controlled trial
- Primary Purpose
- Treatment
- Masking
- Blinded (masking used)
Eligibility Criteria
- Ages
- 18 Years to 70 Years (—)
- Sex
- All
Inclusion Criteria
- •Healthy control and Huntington's disease participants aged 18-70 will be eligible barring they do not violate any of the exclusion criteria.
Exclusion Criteria
- •Exclusion criteria for all participants includes; diagnosis of any other major neurological disorder, traumatic brain injury, drug or alcohol dependency (in the last 3 months), recent diagnosis of major depression or psychosis, consumption of oral antibiotics (in the past 6 months), high daily consumption of probiotic or fermented foods (foods preserved in high amounts of bacteria) within six weeks prior to the study. Further exclusion includes hospitalised patients with a central venous catheter, people with allergies to yeast, people with a diagnosis of Irritable Bowel Syndrome, Celiac's disease or Crohn's disease and people who are severely ill and/or immunocompromised.
Investigators
Similar Trials
Completed
Phase 4
The Impact of Probiotics on Gut Microbiota and Non-Alcoholic Fatty Liver Disease (NAFLD) ProgressioPACTR202204591594284Tanta University84
Recruiting
Not Applicable
Evaluation of the use of Probiotics in the intestinal flora, nutritional status and immune system of patients who underwent Surgery to Remove the Stomach for Gastric CancerGastric NeoplasmsGastrectomyG06.591.375RBR-5vyr8bpFAM- Universidade Federal do Amazonas
Recruiting
Not Applicable
The effect of probiotics on intestinal microbiotaIRCT20220406054437N2Shahid Beheshti University of Medical Sciences50
Recruiting
Not Applicable
Effect of the use of beneficial bacteria on the intestinal microbiota and on nutritional, biochemical and clinical indicators of patients who underwent stomach reduction surgeryObesity, Bariatric surgery, Gastrointestinal Microbiome, DysbiosisRBR-4sqhpppniversidade Federal do Paraná
Recruiting
Not Applicable
Effect of probiotics on gut microbiome and paiIRCT20110510006431N4Shahid Beheshti University of Medical Sciences80