Avaliação in Vivo do Potencial cariogênico e Erosivo de Bebidas e Medicamentos pediátricos líquidos Intra-orais
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Evaluation of group respiratory, nutritional and endocrine pediatric medicines effect on dental biofilm pH
研究概览
简要总结
The aims of this study were to determine the sucrose and liquid oral pediatric medicines of long-term effect on dental biofilm pH to evaluate the cariogenic potential in vivo.
详细描述
Te study was carried out with 12 subjects that were refrained from brushing their teeth for 28 h and did not eat or drink for at least 3 h prior to each appointment. Dental biofilm pH was measured in the cervical and proximal regions of anterior teeth with beetrode-type microelectrode coupled to a potentiometer. The biofilm was submitted nine paediatric medicines a long term and sucrose (negative control). pH measurements were taken at baseline to determine resting plaque pH and at time interval 5, 10, 15, 20, 25 and 30 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 22 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18 to 22 years;
- •Having Oral hygiene adequate (OHI<1.1);
- •Having 20 natural teeth incluing molar;
- •Not havind oral disease.
排除标准
- •Biofilm baseline pH > 5,5;
- •Not signature consent term;
- •Using orthodontic appliance;
- •Having used medicines last 3 months;
- •Pregant woman.
结局指标
主要结局
Evaluation of group respiratory, nutritional and endocrine pediatric medicines effect on dental biofilm pH
时间窗: 6 months
pH was measured in the cervical and proximal regions of anterior teeth dental biofilm with beetrode-type microelectrode coupled to a potentiometer
次要结局
- Evaluation of sucrose antibiotic group and control negative group effect on dental biofilm(12 months)
研究者
Fabio Correia Sampaio
PhD
Federal University of Paraíba