Comparison of the effect of cyclosporine and etanercept on Toxic epidermal necrolysis
Phase 2
- Conditions
- toxic epidermal necrolysis.Toxic epidermal necrolysis [Lyell]L51.2
- Registration Number
- IRCT20191020045169N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Patients with toxic epidermal necrolysis confirmed by a dermatologist.
Exclusion Criteria
patients with any acquired or congenital immune deficiency.
patients with stage 3 or 4 of heart failure.
patients with uncontrolled hypertension.
patients with renal failure.
patients with known hypersensitivity to these drugs.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eisions re-epithelialization of the toxic epidermal necrolysis. Timepoint: daily, during patients admission. Method of measurement: by dermatologist examination and taking standard pictures from patients lesions.
- Secondary Outcome Measures
Name Time Method Mortality rate of the patients. Timepoint: During their admission in the hospital. Method of measurement: SCORTEN index.