Cut-off Values and Adjustments for Diagnosing Sarcopenia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Hacettepe University
- Enrollment
- 292
- Locations
- 1
- Primary Endpoint
- Muscle thickness
Study Overview
Brief Summary
The loss of muscle mass is one of the major diagnostic criteria for sarcopenia. Many methods are also used for the definition of sarcopenia. However there is no information about cut-off values in this respect in the literature. Therefore, the aim of this study is to determine the cut-off values of this ratio for confirming the diagnosis of sarcopenia.
Detailed Description
Decreases in total skeletal muscle mass are accepted to be necessary for confirming the diagnosis of sarcopenia. Many methods are also used for the definition of sarcopenia.
However, ultrasound measurements has a high sensitivity and specify for confirming the diagnosis of sarcopenia. However there is no information about cut-off values in this respect in the literature. Therefore, the aim of this study is to determine the cut-off values of this ratio for confirming the diagnosis of sarcopenia.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Screening
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •To be a volunteer to participate
- •To be an aged 18-90 years old.
Exclusion Criteria
- •Walking with assist device
- •Having a visual deficits
- •Having an undergone orthopedic surgery
- •Having a cardiac pacemaker
- •Having a hypothyroidism, diabetes mellitus, renal/hepatic failure
Arms & Interventions
Control group:young
Sixty older subjects will be evaluated in this study.
Intervention: Ultrasonographic evaluation (Other)
Control Group:Middle-aged
Sixty middle-aged subjects will be evaluated in this study.
Intervention: Ultrasonographic evaluation (Other)
Experimental group:older
Sixty older subjects will be evaluated in this study.
Intervention: Ultrasonographic evaluation (Other)
Outcomes
Primary Outcomes
Muscle thickness
Time Frame: 30 minutes
Muscle thickness in millimeters by Ultrasound.
Skeletal muscle mass
Time Frame: 2 minutes
Skeletal muscle mass will be evaluated by bioelectrical impedance analysis.The unit of measure is kg.
Secondary Outcomes
- Muscle strength(15 minutes)
- Peripheral strength(1 minutes)
- Physical function(5 minutes)
- Anthropometric assessments(5 minutes)
- Balance(1 minute)
- Body mass index(1 minute)
Investigators
Ozden Ozkal
Principal Investigator
Hacettepe University