Omega-3 Fatty Acid Intake and Risk of Colorectal Adenoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 798
- 试验地点
- 1
- 主要终点
- Incidence of Colorectal adenoma
研究概览
简要总结
Patients aged >40 years who underwent elective colonoscopies were recruited from ten institutions. Patients with a history of colorectal cancer or long-term dietary interventions were excluded. Participants completed a food frequency questionnaire (FFQ) prior to endoscopy. FFQ data were analyzed using energy-, age-, sex-, and body mass index-adjusted models; the dietary supplemental omega-3 intake was analyzed separately. Colonoscopy outcome data, including the adenoma number, pathology, and location, were collected. Participants were stratified into omega-3 consumption quartiles to assess colorectal adenoma incidence trends using P for trend analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients aged more than 40 years of age, scheduled for elective colonoscopy.
排除标准
- •inflammatory bowel diseases
- •history of colorectal neoplasms
- •prior gastrointestinal surgery
- •substance abuse including alcohol
- •an inability to complete the survey due to emergency endoscopy
- •cognitive impairments and those undergoing significant dietary modifications
结局指标
主要结局
Incidence of Colorectal adenoma
时间窗: at the completion of the colonoscopy procedure
among groups with different omega-3 intake levels
次要结局
未报告次要终点
研究者
Sang Hoon Kim
Assistant Professor
Chung-Ang University