Effect of opportunistic salpingectomy on ovarian reserve A quasi experimental study

Opportunistic salpingectomy, the surgical removal of both non diseased fallopian tubes, performed for various benign gynaecological indications such as fibroid uterus, adenomyosis and as tubal sterilization, and as a prophylactic procedure in women at average risk for ovarian or tubal cancers. While this procedure is generally considered safe and effective, growing attention is being directed toward its potential impact on ovarian function. The ovaries and fallopian tubes share a close anatomical and vascular relationship. The concern that salpingectomy might compromise ovarian blood supply and thus impair ovarian function has prompted several studies.

 Ovarian dysfunction, often characterized by altered hormone levels, decreased ovarian reserve, and changes in menstrual regularity, can have significant implications for a woman’s reproductive and overall health. This thesis aims to investigate the effects of opportunistic salpingectomy on ovarian function, examining hormonal profiles, ovarian reserve markers such as anti-Müllerian hormone (AMH) and clinical outcomes related to ovarian reserve and menopause onset.Understanding whether salpingectomy adversely affects ovarian health is essential in guiding clinical decisions, especially in women of reproductive age or those at risk of early ovarian insufficiency.

Through a comprehensive analysis of available clinical data and comparison with non-salpingectomy controls, this study seeks to clarify whether opportunistic salpingectomy poses a risk to ovarian function, and under what circumstances such risks might be mitigated.