Effect of intramuscular corticosteroid injection on the post-operative swelling, trismus and pain following lower third molar surgery

Phase 1

• Conditions: post-operative swelling, trismus, pain; Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Dentistry [E06]

• Registration Number: EUCTR2018-004083-62-HU
• Lead Sponsor: Semmelweis University, Oro-Maxillofacial Surgery and Stomatology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-05
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

-on both sides existing lower wisdom teeth, in deeper impaction and similar position
-between the age of 18 and 50
-healthy
-not receiving any medication that can affect the treatment
-good oral hygiene
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

-smoking
-poor oral hygiene
-receiving medication that can affect the treatment
-disease or general state that can affect the treatment
-symptoms of inflammation in the surgical area
-if the patient can not appear on the control examinations

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: The objective of this study is to evaluate the efficacy of intramasseteric corticosteroid (methylprednisolone) injection on post-operative swelling, trismus and pain after mandibular impacted third molar surgery.;Secondary Objective: To evaluate the efficacy of intramasseteric corticosteroid (methylprednisolone) injection on post-operative trismus and pain.;Primary end point(s): -;Timepoint(s) of evaluation of this end point: -

Secondary Outcome Measures

Name	Time	Method
Secondary end point(s): -;Timepoint(s) of evaluation of this end point: -