Independent and Combined Effects of Aerobic and Resistance Training on Blood Pressure

Not Applicable

Completed

• Conditions: Cardiovascular Risk Factor
• Interventions: Behavioral: Aerobic Exercise; Behavioral: Resistance Exercise; Behavioral: Combined aerobic and resistance exercise

• Registration Number: NCT03734146
• Lead Sponsor: Iowa State University

Brief Summary

We compared the effects of 8 weeks of aerobic exercise only, resistance exercise only, or a combination of both on blood pressure in overweight or obese middle-aged adults with elevated blood pressure. Participants engaged in supervised exercise sessions 3 times per week for 60 minutes each session. Outcomes were assessed at baseline and after the 8-week intervention. Extra-intervention physical activity and diet were also assessed.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07-15
• Primary Completion: 2014-12-19
• Study Completion: 2014-12-19
• Status Verified: 2018-10
• Study First Submitted: 2018-10-31
• Study First Submitted QC: 2018-11-05
• Last Update Submitted: 2018-11-05
• Study First Posted: 2018-11-07
• Last Update Posted: 2018-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

• Systolic/diastolic blood pressure of 120-159/80-99 mm Hg
• Non-smoking
• Overweight or obese, with a body mass index of 25-40 kg/m2
• Inactive--not meeting the aerobic or resistance physical activity guidelines, which means engaging in less than 150 minutes/wk of moderate intensity aerobic exercise and less than 2 days per week of resistance training over the past 3 months.

Exclusion Criteria

• Unstable coronary heart disease or decompensated heart failure
• Severe pulmonary hypertension or aortic stenosis
• Acute myocarditis, endocarditis, pericarditis, or aortic dissection
• Other medical condition that is life-threatening or that can interfere or be aggravated by the exercise training such as cancer, uncontrolled diabetes, severe pain or mobility limitations.
• Premenopausal women or postmenopausal women taking hormonal replacement therapy
• Pregnant women or anticipated pregnancy via IVF or other medical procedures during the course of the intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic exercise (AE)	Aerobic Exercise	Engage in supervised aerobic exercise for 60 minutes on 3 days per week for 8 weeks. Exercise is performed on a recumbent bike or treadmill at 50-80% of their heart rate reserve.
Resistance exercise (RE)	Resistance Exercise	Engage in supervised resistance exercise for 60 minutes on 3 days per week for 8 weeks. Exercise consists of 3 sets of 8-12 repetitions of 12 exercises for the major muscle groups.
Combined Resistance and Aerobic Exercise	Combined aerobic and resistance exercise	Engage in supervised aerobic resistance exercise for 60 minutes on 3 days per week for 8 weeks. Exercise consists of 30 min aerobic exercise at 50-80% heart rate reserve and 30 min of resistance exercise comprising 2 sets of 8-12 repetitions of 9 exercises for the major muscle groups.

Primary Outcome Measures

Name	Time	Method
Change in resting blood pressure	Immediately before and after the 8 week intervention	resting systolic and diastolic blood pressure