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临床试验/NCT03734146
NCT03734146已完成不适用

Independent and Combined Effects of Aerobic and Resistance Training on Blood Pressure

Iowa State University0 个研究点目标入组 69 人开始时间: 2014年7月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
69
主要终点
Change in resting blood pressure

研究概览

简要总结

We compared the effects of 8 weeks of aerobic exercise only, resistance exercise only, or a combination of both on blood pressure in overweight or obese middle-aged adults with elevated blood pressure. Participants engaged in supervised exercise sessions 3 times per week for 60 minutes each session. Outcomes were assessed at baseline and after the 8-week intervention. Extra-intervention physical activity and diet were also assessed.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Outcomes Assessor)

盲法说明

The outcomes assessor was blinded to treatment group allocation.

入排标准

年龄范围
45 Years 至 74 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Systolic/diastolic blood pressure of 120-159/80-99 mm Hg
  • Non-smoking
  • Overweight or obese, with a body mass index of 25-40 kg/m2
  • Inactive--not meeting the aerobic or resistance physical activity guidelines, which means engaging in less than 150 minutes/wk of moderate intensity aerobic exercise and less than 2 days per week of resistance training over the past 3 months.

排除标准

  • Unstable coronary heart disease or decompensated heart failure
  • Severe pulmonary hypertension or aortic stenosis
  • Acute myocarditis, endocarditis, pericarditis, or aortic dissection
  • Other medical condition that is life-threatening or that can interfere or be aggravated by the exercise training such as cancer, uncontrolled diabetes, severe pain or mobility limitations.
  • Premenopausal women or postmenopausal women taking hormonal replacement therapy
  • Pregnant women or anticipated pregnancy via IVF or other medical procedures during the course of the intervention

研究组 & 干预措施

Aerobic exercise (AE)

Experimental

Engage in supervised aerobic exercise for 60 minutes on 3 days per week for 8 weeks. Exercise is performed on a recumbent bike or treadmill at 50-80% of their heart rate reserve.

干预措施: Aerobic Exercise (Behavioral)

Resistance exercise (RE)

Experimental

Engage in supervised resistance exercise for 60 minutes on 3 days per week for 8 weeks. Exercise consists of 3 sets of 8-12 repetitions of 12 exercises for the major muscle groups.

干预措施: Resistance Exercise (Behavioral)

Combined Resistance and Aerobic Exercise

Experimental

Engage in supervised aerobic resistance exercise for 60 minutes on 3 days per week for 8 weeks. Exercise consists of 30 min aerobic exercise at 50-80% heart rate reserve and 30 min of resistance exercise comprising 2 sets of 8-12 repetitions of 9 exercises for the major muscle groups.

干预措施: Combined aerobic and resistance exercise (Behavioral)

No training control

No Intervention

No exercise training. Participants will refrain from any moderate-vigorous exercise or resistance training for 8 weeks.

结局指标

主要结局

Change in resting blood pressure

时间窗: Immediately before and after the 8 week intervention

resting systolic and diastolic blood pressure

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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