Breath-hold Cardiac Hybrid SPECT/CCTA

Not Applicable

Completed

• Conditions: Coronary Artery Disease
• Interventions: Device: Breathhold SPECT-MPI; Device: Standard freebreathing SPECT-MPI; Device: Coronary CT angiography

• Registration Number: NCT02469051
• Lead Sponsor: University of Zurich

Brief Summary

This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05
• Study First Submitted: 2015-05-13
• Study First Submitted QC: 2015-06-08
• Study First Posted: 2015-06-11
• Status Verified: 2016-05
• Primary Completion: 2016-05
• Study Completion: 2016-05
• Last Update Submitted: 2016-05-10
• Last Update Posted: 2016-05-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Referral for cardiac hybrid SPECT/CCTA
• Male and female subjects 18 years of age or older
• Written informed consent by the participant after information about the project

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Exclusion Criteria

• Contraindications for coronary CT angiography (including renal failure with a GFR <30ml/min/1.73m2, allergies to iodinated contrast agents)
• Pregnancy or breast-feeding
• Previous coronary revascularisation
• Inability to follow the examination procedure (e.g. due to language barriers, severe mental disease etc

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI	Coronary CT angiography	-
Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI	Breathhold SPECT-MPI	-
Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI	Standard freebreathing SPECT-MPI	-

Primary Outcome Measures

Name	Time	Method
Number of image artefacts	1 day
Image quality as visually assessed on a Likert scale	1 day

Trial Locations

Locations (1)

Department of Nuclear Medicine, University Hospital Zurich; 🇨🇭 Zurich, Switzerland