Effect of Robot Rehabilitation Exercise Training on Motor Control After Stroke
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Columbia University
- Enrollment
- 9
- Locations
- 1
- Primary Endpoint
- Change in Arm Motor Control From Baseline Measured as Average Squared Mahalanobis Distance
Study Overview
Brief Summary
Stroke is a leading cause of neurological disability worldwide, often causing significant weakening and paresis of the affected arm. National spending on post-stroke rehabilitation is project to expand 20% to 35% through 2010. As a new tool for therapists, robotic stroke therapy devices have the potential to be a cost-effective device aid to physical therapy and enable novel modes of exercise not currently available. While recent studies have shown chronic patients benefit from repetitive practice, it is not clear whether they improved via a reduction in impairment or increased functional compensation because there is a lack of standard treatment and scales to assess rehabilitation efficacy in chronic stroke patients. This study aims to reconcile difference performance measurements in robotic rehabilitation to assess the outcome of robotic rehabilitation training.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 21 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Hemiparesis of the upper extremity
- •Diagnosis of a first clinically apparent ischemic stroke at least 6 months prior to study entry
- •Age 18 years or older
- •Ability to sit and be active for an hour on a chair (or wheelchair) without cardiac, respiratory disturbances and/or pain.
Exclusion Criteria
- •Inability to understand and/or follow instructions
- •Pain in shoulder or arm
- •Other neurological or musculoskeletal target organ disorder
- •Inability to give informed consent personally
- •Previous or current contracture of the upper extremity
Arms & Interventions
Robot arm rehabilitation therapy
Arm training using the ReoGo robotic device, 3 times a week for 3 weeks.
Intervention: Robotic arm therapy (Device)
Outcomes
Primary Outcomes
Change in Arm Motor Control From Baseline Measured as Average Squared Mahalanobis Distance
Time Frame: From baseline to within 1 week post-therapy
Arm motor control was assessed through analysis of reaching movements to targets. We derive a measure of arm motor control using functional principal components analysis of reaching trajectories (average squared Mahalanobis distance). This is a unitless measure and lower change values reflect improvement in motor control, while a higher change value reflect a worsening in motor control.
Secondary Outcomes
- Fugl-Meyer (FM) Upper Extremity Motor Assessment(baseline (1 and 3 weeks prior to therapy), within 1 week after therapy, 3 weeks after therapy)
- Action Research Arm Test(baseline (1 and 3 weeks prior to therapy), within 1 week after therapy, 3 weeks after therapy)