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Clinical Trials/NCT00444756
NCT00444756
Completed
Phase 4

Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Peripheral Intravenous Catheterization in Children

Norton Healthcare1 site in 1 country70 target enrollmentApril 2005
ConditionsPain

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Pain
Sponsor
Norton Healthcare
Enrollment
70
Locations
1
Primary Endpoint
VAS pain scores for the PIV insertion as judged by the patients and the blinded observer.
Status
Completed
Last Updated
19 years ago

Overview

Brief Summary

This trial is a comparison of the anesthetic effectiveness of J-Tip needle-free jet injection of 1% buffered lidocaine to the anesthetic effectiveness of topical 4% ELA-Max for peripheral intravenous catheter (PIV) insertion. The researchers hypothesize that the jet injection of lidocaine will provide superior anesthesia to the ELA-Max prior to PIV insertion.

Detailed Description

A prospective, block-randomized, controlled trial comparing J-Tip jet injection of 1% buffered lidocaine to a 30-minute application of 4% ELA-Max for topical anesthesia in children 8-15 years old presenting to a tertiary care pediatric emergency department for PIV insertion. All subjects recorded self-reported Visual Analogue Scale (VAS) scores for pain at time of enrollment and pain of PIV insertion. Jet injection subjects also recorded pain of jet injection. Subjects were videotaped during jet injection and PIV insertion. Videotapes were reviewed by a single blinded reviewer for observer-reported VAS pain scores for jet injection and PIV insertion.

Registry
clinicaltrials.gov
Start Date
April 2005
End Date
April 2006
Last Updated
19 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Between the ages of 8-15 years requiring a PIV as part of their management in the emergency department.

Exclusion Criteria

  • Excluded from the study if they reported use of analgesic medication within 6 hours of enrollment,
  • Had a Glasgow Coma Score \< 15,
  • A baseline screening VAS pain score \> 20 mm, or
  • A history of skin hypersensitivity or lidocaine allergy,
  • Were incapable of self-reporting a pain score,
  • Had a known neurological condition that alters pain perception,
  • Had methemoglobinemia, or
  • Did not speak or understand English.

Outcomes

Primary Outcomes

VAS pain scores for the PIV insertion as judged by the patients and the blinded observer.

Secondary Outcomes

  • Secondary outcome measures included patient and blinded observer VAS scores for pain of jet injection, patient and blinded observer scores for anxiety of PIV insertion, nursing satisfaction of placing the PIV with jet injection or ELA-Maxâ, nursing diffi

Study Sites (1)

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