The TURN trial, Transplantation of faeces in Ulcerative colitis; Restoring Nature's homeostasis.
Completed
- Conditions
- ulcerative colitis, colitis ulcerosa, IBD
- Registration Number
- NL-OMON23236
- Lead Sponsor
- Academic Medical Center (AMC)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Patients 18 years or older;
2. Established ulcerative colitis with known involvement of the left colon;
Exclusion Criteria
1. Condition leading to profound immunosuppression;
2. Anti-TNF treatment in preceding 2 mths;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Co-primary endpoint of clinical remission, as well as reduction of Mayo endoscopic inflammation score at 12 weeks after treatment.
- Secondary Outcome Measures
Name Time Method 1. SCCAI score reduction at t=6 weeks;<br /><br>2. intra individual changes in faecal samples and mucosal biopsies;<br /><br>3. Frequency of bowel movements;<br /><br>4. Time to recurrence.