Biomarkers in Dyspnea
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 34
- Locations
- 1
- Primary Endpoint
- Biomakers in dyspnea
Study Overview
Brief Summary
To explore biological mechanisms in human model of induced dyspnea, in order to remove the source of dyspnoea, to modify cerebral impact and to allow the development of targeted therapies.
Detailed Description
The aim of the study will be to identify a specific biology and immunology associated with dyspnoea. It will open therapeutic possibilities through a better understanding of the mechanisms of dyspnea.
Healthy volunteers will underwent two types of dyspnea. The subjects will be first familiar with both types of dyspnea and dyspnea measurement scales. Different components of dyspnea will be measured.
Blood tests will be performed at different times (before dyspnea, during dyspnea, 60 and 90 min after dyspnea)
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy volunteers
Exclusion Criteria
- •pregnancy
- •ongoing pain
- •respiratory disease
- •high levels of depression, panic disorder, or other significant mental health problems
- •not fluent in french
Arms & Interventions
Induced dyspnea
Intervention: Induced dyspnea (Other)
Outcomes
Primary Outcomes
Biomakers in dyspnea
Time Frame: 60 minutes
Biomarkers in human model of induced dyspnea
Secondary Outcomes
- Correlation with dyspnea intensity(60 minutes)
- Correlation with dyspnea type(60 minutes)