Comparison of Efficacy Permethrin topical Cream in Combination with Doxycycline Tablet with Ivermectin topical Cream in Combination with Doxycycline Tablet in Treatment of cutaneus disease Rosacea Patients
- Conditions
- Rosacea papulopustular disease.
- Registration Number
- IRCT20210729052010N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 40
Diagnosis of typical papulopustular rosacea according two dermatologists and performance biopsy if rosacea is suspected
No treatment with topical steroids or other topical treatment during 14 days before starting study
No treatment with any systemic drugs by known effect on inflammation responses during 30 days before starting study
No treatment with topical retinoids during 30 days ago or systemic retinoids during 180 days before starting study
No treatment by physical modality that effect on rosacea lesions during 30 days before starting study
Absence of other cutaneous diseases that interfere with assessment lesions related to rosacea
Absence of comedon, cyst and scar that benefit to diagnosis of acne vulgaris
Absence of pregnancy and breastfeeding
Less than 18 years
Male gender
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increase or decrease number and severity after use Ivermectin 1% cream or permetrin 5% cream. Timepoint: 0,6 and 12 weeks after starting treatment. Method of measurement: Photography from lesions and remission of lesions.
- Secondary Outcome Measures
Name Time Method