Management of heart failure in India
Not Applicable
- Conditions
- Health Condition 1: I509- Heart failure, unspecified
- Registration Number
- CTRI/2021/11/037797
- Lead Sponsor
- Sree Chitra Tirunal Institute for Medical Sciences and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Decompensated heart failure with LVEF <40%. Potential participants must meet the standard
definition of heart failure based on the European Society of Cardiology Criteria. Echo-cardiography based assessment of LVEF is an essential criteria. Heart failure probability will be assessed based on clinical history,
physical examination and ECG abnormality. Assessment of natruretic peptides will not be an essential criteria.
Exclusion Criteria
Bed-ridden patients and those who are not able to provide written informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of days alive and out-of hospital (DAOH) during the two-year follow-up period. The DAOH is a <br/ ><br>patient-centred outcome, which accounts for multiple events over the course of a study period, weights death <br/ ><br>more than hospitalization, and deaths occurring early more than those occurring later. It is a pragmatic indicator <br/ ><br>that combines two important outcome measures in heart failure.Timepoint: TWO-YEAR
- Secondary Outcome Measures
Name Time Method a composite endpoint of mortality (all-cause) or hospitalization (24 hours)Timepoint: TWO-YEAR;Adherence to Guideline Directed Medical TreatmentTimepoint: ONE-YEAR and TWO-YEAR;Quality of lifeTimepoint: Six-months, One-year, Two-year;six minutes walking distanceTimepoint: ONE AND TWO-YEAR