NCT00428428已完成2 期
Pharmacological Modulation of the Intrarenal Pressure During Endourological Procedures in the Upper Urinary Tract
Fredericia Hosptial1 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2007年2月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- pelvic pressure
研究概览
简要总结
The purpose of the study is to examine the effect of endoluminally administrated isoproterenol on pelvic pressure increase during flexible ureterorenoscopy in 14 humans. We propose that isoproterenol has potential of reducing intrarenal pressure during ureterorenoscopies. Lower intrarenal pressures may have the advantage of facilitating the procedure and reducing intraoperative complications as bleeding and infections.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Indication for ureterorenoscopy
- •Age> 18 years
- •Normal blood pressure
排除标准
- •Malignant disease in the upper urinary tract
- •Heart disease
- •Allergy to Isoproterenol
- •Use of α-blocking or β-blocking medicine
- •Use of Calcium-antagonists
- •Use of NSAIDs the last 48 hours
- •Present stone or JJ-stent in the ureter
- •Neurologic disease in the bladder
- •Pregnancy
- •Nursing mothers
研究组 & 干预措施
1
Placebo Comparator
Saline irrigation
干预措施: Isoproterenol (Drug)
2
Active Comparator
ISO irrigation
干预措施: Isoproterenol (Drug)
结局指标
主要结局
pelvic pressure
次要结局
未报告次要终点
研究者
研究点 (1)
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