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Clinical Trials/NCT01726179
NCT01726179
Completed
Not Applicable

Efficacy of Resin Infiltration of Proximal Caries Lesions in Primary Molars: Randomized Clinical Trial

DMG Dental Material Gesellschaft mbH1 site in 1 country50 target enrollmentDecember 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dental Health
Sponsor
DMG Dental Material Gesellschaft mbH
Enrollment
50
Locations
1
Primary Endpoint
Caries progression rate
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The goal of the project is to investigate the clinical efficacy of management of early caries lesions by resin infiltration and to further scrutinize the patient stress experiences.

Detailed Description

The aim of this study is to test the clinical efficacy of caries infiltration to arrest proximal caries lesions in primary molars. It was hypothesized that infiltrated lesions (test lesions) will progress significantly less than non infiltrated lesions (control lesions). Additionally, it was hypothesized that dental anxiety and stress related to caries infiltration will be significantly less than dental anxiety related to a conventional restorative procedure. The study will be a controlled clinical trial with a split mouth design and blind evaluation of the outcome (caries progression). Caries progression will be evaluated annually, 12, 24, and 36 months after treatment.

Registry
clinicaltrials.gov
Start Date
December 2013
End Date
December 2018
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • children with one tooth surface with active caries lesions
  • two primary molars with proximal lesion detected on the x-ray (scores 2 (E2) or 3 (D1) in Mejàre et al. scoring system with less depth
  • asigned informed consent.

Exclusion Criteria

  • children who do not cooperate during dental appointments
  • primary molars supposed to exfoliate in less than two years
  • lesions showing obvious cavitation or clear sings of inactivity

Outcomes

Primary Outcomes

Caries progression rate

Time Frame: 1 year

Radiographic evaluation of infiltrated and control caries lesions to evaluate caries progression. This is done by pairwise comparison of digital bitewing radiographs by one calibrated, blinded examiner.

Secondary Outcomes

  • Caries progression rate(2 years, 3 years)
  • Stress reaction during treatment(Immediate)
  • Caries risk(Baseline, 6 months, 1 year, 2 years, 3 years)

Study Sites (1)

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