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Clinical Trials/NCT01983527
NCT01983527
Unknown
Not Applicable

A Prospective Randomized 3-arm Trial Comparing Intra-articular Corticosteroid Injection vs Arthrographic Distention vs Arthrographic Distention Plus Intra-articular Corticosteroid Injection in the Treatment of Adhesive Capsulitis

Imelda Hospital, Bonheiden1 site in 1 country132 target enrollmentDecember 2013

Overview

Phase
Not Applicable
Intervention
Arthrographic distention
Conditions
Adhesive Capsulitis
Sponsor
Imelda Hospital, Bonheiden
Enrollment
132
Locations
1
Primary Endpoint
Shoulder pain and disability index(SPADI)
Last Updated
12 years ago

Overview

Brief Summary

Arthrographic distention of the shoulder joint is an increasingly popular treatment option in the management of patients with frozen shoulder. Most have included the intra-articular injection of a corticosteroid as part of the procedure, but it is not known if this is necessary. It is also not known whether arthrographic distention using steroid and saline is better than intra-articular steroid injection alone.

The purpose of this study is to determine whether there is an additional benefit in the combination of arthrographic distention plus intra-articular corticosteroid injection compared to arthrographic distention or intra-articular corticosteroid injection alone.

Registry
clinicaltrials.gov
Start Date
December 2013
End Date
November 2015
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Imelda Hospital, Bonheiden
Responsible Party
Principal Investigator
Principal Investigator

Symons Rolf

Symons Rolf, MD

Imelda Hospital, Bonheiden

Eligibility Criteria

Inclusion Criteria

  • Pain and stiffness in predominantly 1 shoulder for 4 weeks or longer
  • Restriction of passive motion of greater than 30° in 2 or more planes of movement (measured to onset of pain with goniometer)

Exclusion Criteria

  • Previous arthrographic distention and/or corticosteroid injection
  • Systemic inflammatory joint disease
  • Radiological evidence of osteoarthritis of the shoulder or fracture
  • Signs of a complete rotator cuff tear
  • Contraindications to arthrogram and/or distention
  • Lack of written informed consent

Arms & Interventions

Arthrographic distention + intra-articular corticosteroid

Arthrographic distention of the glenohumeral joint with injection of 5 ml contrast, 1 ml (40 mg) Depo Medrol(Methylprednisolone Acetate Injectable Suspension), 15 ml local anaesthetic (Prilocaine) and up to 15 ml saline.

Intervention: Arthrographic distention

Arthrographic distention + intra-articular corticosteroid

Arthrographic distention of the glenohumeral joint with injection of 5 ml contrast, 1 ml (40 mg) Depo Medrol(Methylprednisolone Acetate Injectable Suspension), 15 ml local anaesthetic (Prilocaine) and up to 15 ml saline.

Intervention: Intra-articular corticosteroid Depo Medrol

Arthrographic distention

Arthrographic distention of the glenohumeral joint with injection of 5 ml contrast, 15 ml local anaesthetic (Prilocaine) and up to 15 ml saline.

Intervention: Arthrographic distention

Intra-articular corticosteroid

Arthrographic pseudodistention of the glenohumeral joint with injection of 5 ml contrast and 1 ml (40 mg) Depo Medrol(Methylprednisolone Acetate Injectable Suspension).

Intervention: Intra-articular corticosteroid Depo Medrol

Outcomes

Primary Outcomes

Shoulder pain and disability index(SPADI)

Time Frame: 4 weeks

Secondary Outcomes

  • Shoulder pain and disability index (SPADI)(weekly for a period of 3 months plus at follow-up (4 months and 12 months))
  • Range of motion(4 weeks, 4 months and 12 months)
  • Overall pain score(weekly for a period of 3 months, plus at follow-up (4 months and 12 months))

Study Sites (1)

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