An Open Label Randomised Comparative Clinical Study to Evaluate The efficacy of Chakramarda Ointment And Itraconazole in the management of Dadru(TINEA)
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Efficacy of Chakramarda ointment when compared with Itraconazole ointment in fungal infection with 5D pruritus scale and KOH biomarker
研究概览
简要总结
Skin is the largest superficial covering of the body. In Ayurveda, all skin diseases are included in *kushtha**roga.*Kustha is one of the Ashtamahagada mentioned by Acharyas. Kustha is further categorized as a Maha and *Kshudra Kushta.*Kushta is produced invariably by the vitiation of the 7 factors i.e. 3 doshas and 4 dushya. In Ayurved skin fungal infection is termed as Dadru. It is one of the most common Twak vikara affecting all the age groups of the population. There is no separate mention of nidana, poorvarupa mentioned for kustha can be considered here.
Dadru gradually increases day to day because of improper vihara like uncleanliness of body, sankramika vyadhi. Dadru is kapha-pitta pradhan vyadhi. Acharya Charak mentioned dadru as a kshudra kustha its definition reddish color elevated border pidika in the form of a mandala and itching is known as dadru kustha.Acharya Sushruta and Vagbhata mentioned dadru as a Mahakustha. Dadru is managed by shodhana and Shamana Chikitsa.
Tinea is the name of a group of diseases caused by fungus and it is also known as a ringworm or dermatophyte.Tinea is classified under superficial and deep mycosis. Tinea is a lesion with a central clearing surrounded by an advancing red, scaly, elevated border. One or more lesions may appear. Tinea is a lesion with a central clearing surrounded by an advancing red, scaly, elevated border. One or more lesions may appear. Dermatophyte infections are common worldwide, and dermatophytes are the prevailing causes of fungal infection of the skin, hair, and nails.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •patients having clinical symptoms like kandu,raga,mandala,pidika.
- •tinea corporis,cruris,capitis,pedis,mannum,.
排除标准
- •tinea ungium,tinea barbae.
- •k/c/o uncontrolled hypertension,diabetes mallitus.
- •pregnant and lactating woman.
结局指标
主要结局
Efficacy of Chakramarda ointment when compared with Itraconazole ointment in fungal infection with 5D pruritus scale and KOH biomarker
时间窗: On screening visit,15th day & 30th day.
次要结局
- To study the effect of chakramarda ointment in comparison with itraconazole in management of dadru based on clinical symptoms/5d pruritus scale/biomarker KOH.(On screening visit & 30th day)
研究者
Dr Vatsal N Parmar
Parul Institute of Ayurveda
