Methylenetetrahydrofolate reductase C677T polymorphism in healthy volunteers and its correlation with homocysteine levels related to patients with arterial and venous thrombosis

Department of Clinical Pharmacology0 个研究点目标入组 240 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•control group:
•no history of any major illness in the past six months and no personal history of cardiovascular disease or thrombosis, diabetes mellitus, hypertension and hyperlipidemia
•Patient group: Coronary Artery Disease (CAD) as determined on angiogram, with at least 1 major vessel having more than 75% stenosis or patients with previous history of myocardial infarction or angina pectoris.
•Patients with evidence of Deep vein thrombosis (DVT) involving lower extremities, abdominal vein as seen on Doppler studies, cortical venous thrombosis (as seen from MR venography) and Pulmonary Embolism (as seen from CT pulmonary angiography).
•Other eligibility criteria:
•Patients who are,
•1. Attending OPD of Haematology and Cardiology, BYL Nair Hospital
•2. Of either sex between the age group from 25-70 years
•3. Ready to give written informed consent

发起方

Department of Clinical Pharmacology