Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review

Completed

• Conditions: COVID-19; Pregnancy Outcomes; Maternal Health; Neonatal Health

• Registration Number: NCT06677281
• Lead Sponsor: Zahedan University of Medical Sciences

Brief Summary

This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health. The review focuses on key outcomes such as preterm birth, maternal complications, and neonatal health, utilizing comprehensive literature from peer-reviewed journals. By analyzing existing studies, we aim to identify trends and gaps in research regarding COVID-19 and pregnancy. This review is intended to inform healthcare providers and pregnant individuals about potential risks and considerations during the pandemic.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-03
• Primary Completion: 2024-08-15
• Study Completion: 2024-08-25
• Status Verified: 2024-11
• Study First Submitted: 2024-11-05
• Study First Submitted QC: 2024-11-05
• Last Update Submitted: 2024-11-05
• Study First Posted: 2024-11-06
• Last Update Posted: 2024-11-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 1

Inclusion Criteria

• Pregnant individuals diagnosed with COVID-19.
• Studies reporting pregnancy outcomes related to COVID-19 published between January 2020 and the present.
• Articles that include quantitative data on maternal and fetal outcomes.

Exclusion Criteria

• Studies that do not report on COVID-19-related pregnancy outcomes.
• Non-peer-reviewed articles or grey literature.
• Research focusing on non-pregnant populations.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Impact of COVID-19 on Maternal and Neonatal Outcomes	The review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.	This primary outcome measure evaluates the various maternal and neonatal outcomes associated with COVID-19 infection during pregnancy. Key metrics include rates of maternal morbidity, neonatal morbidity, preterm birth, low birth weight, and any documented complications during pregnancy, labor, and delivery. The systematic review aims to synthesize data from available studies to provide a comprehensive understanding of these outcomes and their implications for clinical practice.

Secondary Outcome Measures

Name	Time	Method
Effects of COVID-19 on Pregnancy-Related Complications	The review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.	This secondary outcome measure assesses the frequency and types of pregnancy-related complications associated with COVID-19. This includes conditions such as gestational hypertension, gestational diabetes, placental abruption, and other adverse effects that may arise during the pregnancy period. The review aims to analyze the incidence of these complications in pregnant individuals diagnosed with COVID-19 compared to non-infected counterparts, providing insights into how the virus may impact overall pregnancy health.

Trial Locations

Locations (1)

Zahedan University of Medical Sciences; 🇮🇷 Zahedan, Sistan and Baluchestan, Iran, Islamic Republic of