IRCT20171225038073N1招募中3 期
Evaluation of nephroprotective effects of Melatonin in cancer patients treated with Cisplatin
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •= 18 years of age
- •Cancer patients who receive Cisplatin with =50 mg/m2 of dose in one day and the chemotherapy courses are repeated every 3 weeks
- •Patients who do not use other nephrotoxic chemotherapy drugs
- •Glomerular filtration rate (GFR)>45 ml/min (modification of diet in renal disease (MDRD) formula)
- •Patients with one of lung? head and neck? genitourinary system, gastrointestinal cancers
- •Karnofsky status = 60%
- •Normal liver function
排除标准
- •Kidney cancer
- •Inability to take oral medication
- •Heart failure
- •Active infection
- •The history of using other nephrotoxic drugs (e.g. Vancomycin, Aminoglycoside, Amphotericin and NSAID) within the previous 2 weeks
- •The patients who are using angiotensin-converting-enzyme inhibitor (ACE inhibitor) & angiotensin receptor blockers (ARB) medicines
研究者
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