The effect of topical olive leaf extract 2% and topical acyclovir 5% on facial herpes simplex

Phase 2

• Conditions: herpes simplex facialis.; Herpesviral vesicular dermatitis

• Registration Number: IRCT138808092652N1
• Lead Sponsor: orestan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Having facial herpes simplex, willingness to participate in the study and sign a written consent
Exclusion criteria: Participation in drug therapy including corticosteroids, antiviral drugs and immunosuppressive drugs, immune deficiency, metabolic, chronic, or serious systemic illnesses, simultaneous participation in another research, hypersensitivity to antivirus drugs

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: before treatment, 3 and 6 days after treatment. Method of measurement: severity of pain was scaled by Mcgill-Melzak method.;Itching. Timepoint: before treatment, 3 and 6 days after treatment. Method of measurement: by Mcgill-Melzak method.;Success of treatment. Timepoint: 3 and 6 days after treatment. Method of measurement: percentage of cured patients.;Lesion size. Timepoint: before treatment, 3 and 6 days after treatment. Method of measurement: Using a disposable folding ruler.;Bleeding. Timepoint: before treatment, 3 and 6 days after treatment. Method of measurement: Presence of bleeding.;Color change. Timepoint: before treatment, 3 and 6 days after treatment. Method of measurement: color change comparing to the skin.;Side effects. Timepoint: 3 and 6 days after treatment. Method of measurement: based on patient's complaint.