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Study of Usefulness of Fluorescence in Thiroid Surgery

Not Applicable
Recruiting
Conditions
Thyroid Surgery
Interventions
Procedure: Fluorescence in thyroid surgery
Registration Number
NCT06011369
Lead Sponsor
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Brief Summary

In thyroid surgery, the identification and preservation of the parathyroid glands and their vascularization is essential to avoid postoperative hypoparathyroidism. In this sense, fluorescence technology with autofluorescence (AF) can help us avoid this post-surgical complication. This study aims to determine the advantages offered by fluorescence in thyroid surgery, taking into account various clinical variables.

For this, a randomized study is proposed in patients undergoing thyroid surgery with and without cervical fluorescence.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
260
Inclusion Criteria
  • Total thyroidectomy with/without lymph node dissection
  • Signature of informed consent
Exclusion Criteria
  • Patients under 18 years of age
  • Hemithyroidectomy
  • Reintervention of thyroid surgery

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Fluorescence in thyroid surgeryFluorescence in thyroid surgeryPatients undergoing thyroid surgery with cervical fluorescence.
Primary Outcome Measures
NameTimeMethod
Number of parathyroid glands identified before the use of AF (Autofluorescence)Up to 12 months.

Gland count

Number of glands accidentally removed.Up to 12 months.

Gland count

Number of autotransplanted glands.Up to 12 months.

Gland count

Concentration of PTH and calcium corrected by albumin and/or ionic6,12 Months

Value in analytics

Surgical time.Up to 12 months.

Hours of surgery

Number of previous thyroidectomies performed with FA (Autofluorescence)(learning curve)Up to 12 months.

Number of surgeries using autofluorescence

Type of surgery performedUp to 12 months.

total thyroidectomy/hemithyroidectomy; lymphadenectomy

Number and location of parathyroid glands identified with the use of FA (Autofluorescence)Up to 12 months.

Gland count

Quantification of each parathyroid gland with AF(Autofluorescence)Up to 12 months.

(two determinations in the same parathyroid gland, in total, eight determinations of the parathyroid glands parathyroid, and three determinations in the thyroid gland, the last being in a nodule if it'd exist

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hospital Clínico Universitario Virgen de la Arrixaca

🇪🇸

Murcia, Spain

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