The Association between Pre-treatment Dietary Behavior and Taste Alteration in Thai Head and Neck Cancer Patients Who Underwent Radiotherapy

Not Applicable

Completed

• Conditions: UMAMI THRESHOLD; RADIOTHERAPY; HEAD AND NECK CANCER; head and neck cancer radiation therapytaste alteration; TASTE PREFERENCE; NUTRITION STATUS

• Registration Number: TCTR20170801003
• Lead Sponsor: Research and Education Unit on Sensory Sciences for Better Nutrition, Institute of Nutrition, Mahido

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-05-31
• Study Start: 2017-08-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

- Age over 18 years
- Diagnosed with head and neck cancer
- No history of cancer treatment during the past 6 months
- Have treatment plan for radiotherapy which is expected to have
taste alteration as complication
- Able to communicate in Thai and sign the consent form
- Resided in Thailand during the past 5 years

Exclusion Criteria

- Loss of all taste sensation prior to radiotherapy
- Unable to tolerate the test
- Taking medicines affecting taste as side effects during the past one week prior to radiation, including cyclophosphamide, cisplatin, etoposide, zopiclone, azelastine, emedastine, amiloride, penicillamine, captopril, metronidazole, chlorhexidine, eprosartan

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
changes in recognition thresholds 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r filter paper disc,changes in body weight 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r weight scale,preference in spicy, umami, sweet, salty, sour, bitter before radiation therapy validated questionnaire (Taste-26)

Secondary Outcome Measures

Name	Time	Method
changes in PG-SGA score 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r PG-SGA questionaire and exam,changes in energy intake 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r 3-day dietary record