Comparison of peripheral venous and arterial blood gas in management of patients with respiratory complaints in the emergency department.

Completed

Conditions: Respiratoire klachten veroorzaakt door verschillende onderliggende ziektebeelden
Respiratoiry complaints

Registration Number: NL-OMON48393

Lead Sponsor: Zuyderland Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 155

Inclusion Criteria

Patients (* 18 years) presenting in the ED with dyspnoea, respiratory rate >
20/min or peripheral oxygen saturation < 95%, a reliable saturation measured by
pulse oximetry (measured with the Philips IntelliVue MP30 patient monitor, a
reliable measurement is defined by pulsatile flow with a perfusion indicator
value above 0.3) and an indication, determined by the treating physician, to
determine the acid-base, ventilation and oxygenation status by arterial blood
gas.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
- Not capable to give informed consent within reasonable time after
stabilisation and abating of the accompanying psychological stress, and no
representative available to give informed consent on behalf of the patient.
- Arterial blood gas results are required for other reasons than determining
the acid-base, ventilation and oxygenation status, such as determining the
alveolar to arterial oxygen gradient (A-a gradient).
- No physician or qualified nurse available for ABG sampling.
- Failed ABG or VBG sampling after two attempts.
- Previous participation in the study.

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint is the frequency of alterations in treatment of<br /><br>patients with respiratory complaints in the emergency department (ED) based on<br /><br>venous blood gas (VBG) results compared to treatment based on arterial blood<br /><br>gas (ABG) results. We will assess which alterations in treatment occur, the<br /><br>characteristics of alterations and which ABG results cause the change. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are the agreement between venous and arterial pH,<br /><br>bicarbonate, pCO2, lactate and pO2 and the correlation between venous and<br /><br>arterial pO2 and the peripheral oxygen saturation measured with pulse oximetry. </p><br>