Skip to main content
Clinical Trials/NCT06644599
NCT06644599
Not Yet Recruiting
N/A

Integrated Proactive Wireless Monitoring for Clinical Deterioration: A Stepped Wedge Randomized Trial

King Abdullah International Medical Research Center0 sites13,160 target enrollmentNovember 1, 2025

Overview

Phase
N/A
Intervention
Not specified
Conditions
Inpatient Facililty Diagnoses
Sponsor
King Abdullah International Medical Research Center
Enrollment
13160
Primary Endpoint
Composite endpoint of 30-day in-hospital mortality, cardiac arrest, requirement of vasopressor or intubation
Status
Not Yet Recruiting
Last Updated
8 months ago

Overview

Brief Summary

The study evaluates whether implementing a wireless monitoring system for patients admitted to hospital wards reduces mortality and cardiopulmonary failure.

Detailed Description

The trial is designed as a stepped-wedge cluster RCT. Hospital wards (which constitute clusters in this design) will be randomized to have wireless monitoring, 7 wards at a time, with each 7 wards constituting a sequence. The study consists of 5 periods of two-month sequences followed by a one-month transition time with a phased introduction of the intervention. In the first period, all wards will have no wireless monitoring. After a baseline period of 2 (+1 washout) months, the intervention (monitoring system) will be implemented in a randomly selected new sequence every 3-month period until the intervention is implemented in all sequences.

Registry
clinicaltrials.gov
Start Date
November 1, 2025
End Date
December 1, 2026
Last Updated
8 months ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr Yaseen Arabi

Chairman intensive care unit

King Saud Bin Abdulaziz University for Health Sciences

Eligibility Criteria

Inclusion Criteria

  • Ward level Inpatient wards, defined as wards used to manage adult inpatients.
  • Patient level
  • Aged 14 years or older
  • Checked in as inpatient status to one of the study wards

Exclusion Criteria

  • Cardiology, pediatric, obstetric wards
  • ICUs and emergency departments
  • Operating rooms
  • Outpatient clinics
  • Daycare wards, endoscopy, outpatient procedure areas, hemodialysis units
  • Patient level No commitment for full life support at the time of arrival to the study ward (designated as Do-Not-Resuscitate status)

Outcomes

Primary Outcomes

Composite endpoint of 30-day in-hospital mortality, cardiac arrest, requirement of vasopressor or intubation

Time Frame: 30 days

After hospital admission within 30 days

Secondary Outcomes

  • Cardiac arrest(30 days)
  • Requirement of vasopressors(within 30 days of hospital admission)
  • Requirement of intubation(30 days)
  • Hospital length of stay(90 days)
  • Transfer to ICU(30 days)
  • ICU- free days(30 days)
  • CCRT activation(30 days)

Similar Trials