Application of Frailty Assessment in Elderly Patients Undergoing Gastrointestinal Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gastrointestinal Disease
- Sponsor
- Ziqiang Wang,MD
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Blood loss
- Last Updated
- 5 years ago
Overview
Brief Summary
Patients aged 65 or older under gastrointestinal surgery will be enrolled，the investigators will assess the frailty of these patients by Frailty Index Scale and explore the correlation between the frailty and perioperative adverse events.
Detailed Description
Patients will be assessed by specially trained doctors or nurses after admission, including daily living ability, physiological function, social-psychological status, comorbidities, mental state, grip strength, walking speed. After the assessment, the patients' frailty index was obtained. Moreover, the operation time, intraoperative bleeding loss, perioperative complications, length of stay, hospitalization expenses, readmission rate within 30 days, mortality within 30 days and other outcome indicators of these patients will be recorded. The Main purposes of present study are to verify the feasibility of applying Frailty Index (FI) to assess the degree of frailty in elderly patients undergoing gastrointestinal surgery, compare the difference of perioperative adverse events in elderly patients with different degrees of frailty，find potential indicators for evaluating and predicting the safety of surgery in elderly patients, and provide reference data for the determination of future assessment tools of frailty. The secondary objective is to compare the quality of life and long-term prognosis(only for patients with cancers,including recurrence free survival and overall survival) of elderly patients with different degrees of frailty after gastrointestinal surgery.
Investigators
Ziqiang Wang,MD
Clinical professor
West China Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients whose age not less than 65 years;
- •undergoing operation in gastrointestinal surgery of West China hospital due to gastrointestinal disease.
Exclusion Criteria
- •Those who did not undergo surgery for various reasons;
- •Death before operation
Outcomes
Primary Outcomes
Blood loss
Time Frame: 2 year
intraoperative blood loss
postoperative complications
Time Frame: 2 year
including incision infection，anastomotic leakage，respiratory infection, postoperative bleeding and so on.
The length of stay in intensive care unit (ICU)
Time Frame: 2 year
Time form entry to ICU to return to general ward after the condition is stable.
operative time
Time Frame: 2 year
From the beginning of the skin incision to the end of the last incision was From the beginning of the skin incision to the end of the suture of last incision
The length of hospitalization
Time Frame: 2 year
Time from admission to discharge
Hospital costs
Time Frame: 2 year
Cost of diagnosis and treatment during hospitalization
Readmission rate within 30 days
Time Frame: 2 year
The proportion of patients who are re-hospitalized for postoperative complications after 30 days of discharge in all subjects.
Intraoperative complications
Time Frame: 2 year
Including all the complications in the procedure
Mortality within 30 days
Time Frame: 2 year
death rate within 30 days after surgery in all patients after operation
Secondary Outcomes
- Recurrence-free Survival (RFS)(2 year)
- Overall survival (OS)(2 year)