A comparative clinical trial to study the effect of Darvyadi Niruhabasti and Panchatikta Panchaprasrutik Basti in the management of Kitibha Kushtha(psoriasis)
- Conditions
- Psoriasis. Ayurveda Condition: KITIBAH,
- Registration Number
- CTRI/2022/06/042961
- Lead Sponsor
- Parul Ayurved Hospital
- Brief Summary
Psoriasis is one of the most common dermatological diseases affecting 2% of the World’s population. In India, the prevalence of Psoriasis varies from 0.44% to 2.8%. To date, no proper curative measures are found to treat psoriasis in modern science, so it is necessary to find a safe and effective measure for Psoriasis. Psoriasis has maximum resemblance with the Kitibha kushtha mentioned as a type of Kushtha in Ayurvedic classics so can be treated as per Kushtha chikitsa. As per Ayurveda’s unique treatment, Basti karma here is an attempt to study the efficacy of Darvyadi Niruhabasti and Panchatikta Panchaprasrutik Basti with Madanadi taila Anuvasana Basti in the management of Kitibha Kushtha (Psoriasis).
RESEARCH QUESTION:
Whether the Darvyadi Niruhabasti & Panchatikta Panchaprasrutik Basti with Madanaditaila Anuvasanabasti are effective in the Yogabasti krama in the management of Kitibha kushtha w.s.r. to psoriasis?
AIM:
Comparison of the efficacy of Darvyadi Niruhabasti & Panchatikta Panchaprasrutik Basti along with Madanaditaila Anuvasanabasti in the management of Kitibha kushtha.
OBJECTIVES:
- To determine the effects of Darvyadi Niruhabasti and Madanaditaila Anuvasanabasti in the management of Kitibha kushtha.
- To determine the effects of Panchatikta Panchaprasrutik Basti and Madanaditaila Anuvasanabasti in the management of Kitibha kushtha.
- To compare the efficacy of Darvyadi Niruhabasti & Panchatikta Panchaprasrutik Basti along with Madanaditaila Anuvasanabasti in the management of Kitibha kushtha.
- To evaluate the role of Basti treatment in the management of Kitibha kushtha.
MATERIALS AND METHODS:
- Duration of Study: 18 months
- Study design: Randomized comparative clinical trial
- Purpose of the study will be explained and written informed consent will be taken from every patient.
- SOURCES OF DATA:
1. LITERARY SOURCE: All classical, modern literature and contemporary texts including the journals and websites about the disease, drugs and procedures will be reviewed and documented for the study.
2. PHARMACEUTICAL SOURCE: Madanaditaila for Anuvasanabasti will be prepared in the GMP certified Pharmacy of Parul Institute of Ayurveda. Niruhabasti will be prepared at Parul Ayurveda Hospital as per proper SOPs.
3. CLINICAL SOURCE: Diagnosed cases of Kitibha kushtha, will be selected from OPD and IPD of Parul Ayurveda Hospital, Limda, Vadodara.
TREATMENT GROUPS:
Group A (Trial group) – 20 patients will be administered Darvyadi Niruhabasti and Madanaditaila Anuvasanabasti.
Group B (Control group) – 20 patients will be administered Panchatikta Panchaprasrutik Basti and Madanaditaila Anuvasanabasti.
SUBJECTIVE CRITERIA –
- Shyavavarna
- Kinkhara sparsha
- Parushatva
- Kandu
- Scaling
OBJECTIVE CRITERIA –
- Auspitz sign
- Candle Grease test
- PASI Score
INTERVENTION:
- Yoga Basti: 8 days
| | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- |
| 1st day 2nd day 3rd day4th day 5th day6th day 7th day8th day
| AB NBABNBABNBABAB
Here, AB - Anuvasana Basti, NB - Niruha Basti
- Basti Quantity: 1. Niruha Basti - 550 ml 2. Anuvasana Basti - 70 ml
- Follow up - 15 days after treatment of 8 days
The effect of the Basti (Panchakarma therapy) will be assessed based on the following criteria –
- Samyak Basti Lakshanas
- The retention time of Basti
- Number of purisha vega
- Possible complications after administration of Basti
- Vital data of patients
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 40
- Patients presenting with clinical signs and symptoms of Kitibha Kushtha.
- Kitibha Kushtha patients between the age group of 18 to 70 years.
- Patients of either gender irrespective of caste and religion.
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- Patients having other systemic disorders.
- known case of Hypertension, Carcinoma, Tuberculosis, Infectious diseases and other life threatening disorders. 2. Patients contraindicated for Shodhana such as Pregnant & lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helps in reduction of signs and symptoms of psoriasis and recurrence of the disease will be controlled. 8 days of treatment | After 15 days of treatment follow up
- Secondary Outcome Measures
Name Time Method There will be increased quality of life in psoriasis patients and complications of the disease will be reduced. 25 days
Trial Locations
- Locations (1)
Parul Ayurved Hospital
🇮🇳Vadodara, GUJARAT, India
Parul Ayurved Hospital🇮🇳Vadodara, GUJARAT, IndiaMeghavi Jitendrakumar VaghamshiPrincipal investigator9904709494meghavi.vaghamshi.1010@gmail.com