Core Stability Training in Ambulant Individuals With Multiple Sclerosis: a Multi-centre Randomised Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 7
- 主要终点
- Change in 10 metre timed walk (10MTW)
研究概览
简要总结
The primary purpose of this study is to determine whether a 12 week Pilates based core stability training programme is effective in improving balance, mobility and balance confidence in ambulant individuals with Multiple Sclerosis (MS).
详细描述
The primary purpose of this study is to determine whether a 12 week Pilates based core stability training programme is effective in improving balance, mobility and balance confidence in ambulant individuals with Multiple Sclerosis (MS). The secondary aim is to determine the relative effectiveness of this 12 week Pilates based core stability training programme compared to a standardised physiotherapy exercise programme. Finally we intend to explore the underlying mechanisms of change associated with these exercise interventions by directly measuring changes in muscle thickness and activation in the deep abdominal core stabilising muscles of a sub-set of participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Definite diagnosis of MS, according to McDonald's criteria
- •Aged 18 years or over
- •Able to walk independently with or without use of intermittent or constant unilateral assistance such as walking stick or orthotic brace
排除标准
- •In relapse or relapse in previous three months
- •Any medical condition contra-indicating participation in core stability exercises
- •Score < 6 on the Abbreviated Mental Test, as an indicator of those whose cognitive difficulties could interfere with the informed consent process, or the ability to fully engage in the exercise programme.
- •Current or recent (within past 6 months) participation in core stability exercises
- •Current involvement in another interventional research study
研究组 & 干预措施
Relaxation
干预措施: Relaxation (Other)
Standard Physiotherapy Exercises
干预措施: Standard Physiotherapy Exercises (Other)
Core Stability Training
干预措施: Core Stability Training (Other)
结局指标
主要结局
Change in 10 metre timed walk (10MTW)
时间窗: baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks ( one month follow-up)
次要结局
- Change in Multiple Sclerosis 12-item Walking Scale(baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks (one month follow-up))
- Change in Activities-specific Balance Confidence (ABC) Scale(baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks (one month follow-up))
- Change in Visual Analogue Scale (10 point) to determine "Difficulty in carrying a drink when walking".(baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks ( one month follow-up))
- Change in Functional Reach - forwards and lateral(baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks ( one month follow-up))
研究者
Jenny Freeman
Dr Jenny Freeman
University of Plymouth