The efficacy of vitD3 in patients with ART(Assisted Reproductive Teqchnique) failure
Phase 2
- Conditions
- Patients with IVF Failure.In vitro fertilization
- Registration Number
- IRCT2012120311430N2
- Lead Sponsor
- ?Avicenna research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
infertile women 20-35 years old with two or more previous IVF failure, without using vitamin D and Calcium from 3 months before.
Exclusion criteria:untreated medical disorders; endometriosis; poor responders; hydrosalpinx in ultrasonography; abnormal semen analysis ( Abnormal form>96%,A+B=32%); use of drugs that affect on immune system; thrombophilia (homozygot PAI-I , homozygot C677T, homozygot A1908C, Heterozygot A1908C-C977T); hormonal disorder (FSH>12,PCO); anatomic disorders; genetic disorders and infective disorders
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pregnancy rate. Timepoint: 14 days after embryo transfer. Method of measurement: ßhCG ,14 days after embryo transfer.;Abortion rate. Timepoint: every 2 months. Method of measurement: ßhCG and ultrasonography.
- Secondary Outcome Measures
Name Time Method Quality of embryo. Timepoint: Embryo transfer. Method of measurement: Morfology.;1,25(OH)2D3. Timepoint: Before ovum pick up. Method of measurement: Blood sampling.