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Phase II double-blind, randomised, placebo-controlled study the safety and immunogenicity of H1/IC31 (trademarked), in HIV-infected adults without TB

Not Applicable
Conditions
HIV/AIDS
Tuberculosis
Registration Number
PACTR201105000289276
Lead Sponsor
Statens Serum Institut
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
48
Inclusion Criteria

1. TB negative
2. HIV infected
3. CD4 count greater than 350 cells per ml cubed

Exclusion Criteria

Evidence of or suspected active TB

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the safety of the H1/IC31 (trademarked) TB vaccine in HIV-infected adults;To evaluate the induction of cellular and humoral immunity of the H1/IC31 (trademarked) TB vaccine in HIV-infected adults
Secondary Outcome Measures
NameTimeMethod
To describe the effect of H1/IC31 (trademarked) TB vaccine in HIV-infected adults on CD4+ lymphocyte counts;To describe the effect of H1/IC31 (trademarked) TB vaccine in HIV-infected adults on HIV viral loads
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