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临床试验/CTRI/2018/07/014932
CTRI/2018/07/014932尚未招募Unknown

2-chloroprocaine and bupivacaine for infraumbilical short duration surgeries : a prospective observational study

Dhondiram Dadu Kamble1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2018年1月8日最近更新:

试验速览

阶段
Unknown
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
Duration of anaesthesia an restriction of movement

研究概览

简要总结

Spinal anaesthesia is safe and reliable technique for surgeries of lower abdomen and lower limbs. Nevertheless, some of the characteristics may limit its use for umbilical surgeries, including delayed ambulation, risk of urinary retention. So the choice of local anaesthetic is crucial in ambulatory settings. Short acting local anaesthetic may therefore represent a valid alternative like preservative free  isobaric 2 chloroprocaine.

Preservative free isobaric 2 chloroprocaine is shorter acting and without significant risk of Transient Neurological Symptoms with respect to hyperbaric lidocaine. The recovery is far earlier than bupivacaine and urinary retention is also not observed in most of the patients. Haemodynamic changes are also not much. So we think that chloroprocaine is better for short duration surgeries with better outcome.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Weight 50 to 70 kg ASA GRADE 1 AND 2.

排除标准

  • Spine deformities Prolonged major surgeries Coagulation abnormalities.

结局指标

主要结局

Duration of anaesthesia an restriction of movement

时间窗: End of surgery | At 1.5 hrs after giving spinal | 2 hrs | 2.5 hrs

次要结局

  • Any complications like urinary retension(Transient Neurological Symptoms)

研究者

发起方
Dhondiram Dadu Kamble
申办方类型
Other [family person ]

研究点 (1)

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