expression of inflammatory mediator in skin biopsy of tinea infectio

Not Applicable

• Conditions: Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue

• Registration Number: CTRI/2024/01/061976
• Lead Sponsor: GCSMCH&RC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 March 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

all patients with clinically diagnosed and confirmed with KOH smear examination for tinea/ dermatophytic infection with age 18-60 years who are willing to sign informed consent form.

Exclusion Criteria

A.Patients who are not willing to sign informed consent form.

B.Patients with age less than 18 years and more than 60 years.

C.Pregnant and lactating mothers.

D.Patients with diseases enlisted in point E&F which may interfere with expression of IL-17 in tissue.

E.Cutaneous disorders like- acne, hidradenitis suppurativa, psoriasis, alopecia areata, vitiligo, autoimmune bullous diseases

F.Systemic diseases like- multiple sclerosis, inflammatory bowel disease, systemic lupus erythematosus, asthma, Behcet’s disease, hyper IgE syndrome, systemic sclerosis

G.Preexisting Cardiovascular, pulmonary, hepatic, renal, hematological, gastrointestinal,endocrine, immunologic, musculoskeletal, neurological, or psychiatric disease.

H.Major surgical or medical illness in last 4 weeks before screening, Any concomitant medication for purpose other than dermatophytosis management at presentation or within last 4 weeks before screening.

I.Any concomitant intake of herbal, homeopathic or other alternative therapy at presentation or within last 4 weeks before screening.

J.Alcohol dependence, alcohol abuse or drug abuse within the past year.

K.Moderate to heavy smoking ( >10 cigarettes/day) or consumption of tobacco products

L.Clinically significant illness within 4 weeks before the start of the study

M.Asthma, urticaria or other allergic type reactions after taking any medication.

N.Patient having pre-existing medical condition (DM HT or any other medical condition requiring concomitant medicine.) or diagnosed during screening.

O.Dermatophytosis independently involving scalp (T. Capitis), nail, palm (T. pedis) and sole (T. mannum).

P.Patients having skin lesions with secondary bacterial infections.

Study & Design

• Study Type: Observational
• Study Design: Not specified