Effectiveness of Ayurvedic Formulation Patanjali Typhogrit in subjects with Typhoid Fever.

Phase 3

Recruiting

• Conditions: Other infectious disease. Ayurveda Condition: VISHAJAJVARAH,

• Registration Number: CTRI/2023/09/057896
• Lead Sponsor: Patanjali Research Foundation governed by Patanjali Research Foundation Trust

Brief Summary

This study is a single-arm, open-label, prospective, interventional study. In this study, 50 participants will be enrolled aged 18-75 years. Participants will receive intervention with medication for 45 days. The primary outcome records the changes in the participant’s condition after 45 days of treatment and the secondary outcome involves changes in the values of the Multidimensional Fatigue Inventory (MFI), Visual Analog Scale (VAS)& Patient’s Global Impression of Change (PGIC).

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-28
• Last Update Posted: 2023-09-29

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• 1.Clinically diagnosed with Typhoid fever (Qualitative result as positive on Rapid Typhoid Dot Test Report).
• The subjects who will be diagnosed by physician in clinic or having the history of diagnosed Typhoid fever. 2.Subjects with temperature more than 1000 F 3.Males or Females of age limit 18 years to 75 years. 4.Subjects willing to participate and give consent for the study. 5.Capability for complete compliance and completion of follow-up.

Exclusion Criteria

• 1.Pregnancy or lactation, intent to become pregnant.
• 2.Diagnosis of other bacterial and viral fever than Typhoid fever.
• 3.Subjects not willing to participate and give consent for the study.
• 4.The subject with a known history of any malignancy, uncontrolled diabetes mellitus, psychiatric disorders, or with complications of Cardiovascular diseases, liver diseases or kidney disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
changes in subject’s condition including general health and fever.	Baseline, Day 15, Day 30, Day 45

Secondary Outcome Measures

Name	Time	Method
•To assess the changes in the values of Multidimensional Fatigue Inventory (MFI), Visual Analog Scale (VAS) & Patient’s Global Impression of Change (PGIC)	Baseline, Day 15, Day 30, Day 45

Trial Locations

Locations (2)

Patanjali Wellness Center; 🇮🇳 Hardwar, UTTARANCHAL, India

Patanjali Yoggram; 🇮🇳 Hardwar, UTTARANCHAL, India

Patanjali Wellness Center

🇮🇳Hardwar, UTTARANCHAL, India

Dr Devasena K M

Principal investigator

7012421624

drdevasenabamsmd@gmail.com