A Randomized Controlled Trial of Intramuscular Gonadotropin-Releasing Hormone (GnRH)-analogue Stimulation Test Compared to Subcutaneous Injection to Diagnose in Girls with Central Precocious Puberty
Phase 1
Recruiting
- Conditions
- maximum LH level(tmax) for the diagnosis of CPP girls after GnRH-analogue stimulation testCentral precocious puberty, diagnosis, Intramuscular, GnRH-analogue stimulation test
- Registration Number
- TCTR20240719003
- Lead Sponsor
- Research Affair Faculty of Medicine Chulalonkorn
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 52
Inclusion Criteria
Girls who presented with breast developed before 8 years at KCMH between the years 2024 and 2025 will be recruited.
Exclusion Criteria
Exogenous hormonal use, Congenital adrenal hyperplasia, Peripheral precocious puberty (Adrenal tumor, Ovarian tumor, or cyst, etc.)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the time to the maximum LH level (tmax) at maximum LH level Electrochemiluminescence immunoassay (ECLIA)
- Secondary Outcome Measures
Name Time Method