Assessment of Foot Alignment and Pressure After Correction of Varus Knee by High Tibial Osteotomy or Total Knee Replacement

• Conditions: Varus Deformity

• Registration Number: NCT05314972
• Lead Sponsor: Assiut University

Brief Summary

This study evaluated the change in foot alignment after TKA or HTO by prospectively analyzing the correlation between the knee joint and the foot deformity, the post-operative improvement in the foot deformity, and the long-term post-operative changes in foot alignment.

Detailed Description

The mechanical alignment of the lower extremity is an important consideration in the long-term outcome following total knee arthroplasty (TKA) or high tibial osteotomy (HTO) . Alignment between the hip and the ankle through the knee joint has been used in determining coronal alignment, based on the assumption that weight-bearing forces pass through the centre of the knee joint during neutral mechanical. However, the weight-bearing vector can be affected by hindfoot and midfoot alignment because load is transmitted not from the ankle joint, but from the ground reaction point. Thus hindfoot alignment after knee correction may critically affect the longevity of the prosthesis

Most patients with some degree of knee joint deformity, which in turn may be associated with a deformity of the foot. In fact, an association between varus alignment of the knee joint and valgus alignment of the foot in osteoarthritis patients has been reported. Because the subtalar joint compensates for the knee joint deformity , correction of the deformity after TKA or HTO can affect foot alignment. Improvements in midfoot and hindfoot alignment have been noted in patients with osteoarthritis after correction of deformity. However, foot valgus may also persist, with little improvement after knee correction.

Study Timeline

• Study First Submitted: 2021-12-31
• Status Verified: 2022-03
• Study First Submitted QC: 2022-03-27
• Last Update Submitted: 2022-03-27
• Study First Posted: 2022-04-07
• Last Update Posted: 2022-04-07
• Study Start: 2022-05-01
• Primary Completion: 2023-01-01
• Study Completion: 2023-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• all varus aligned knee admitted to Assiut University Hospitals (Total Knee Arthroplasty or High Tibial Osteotomy) .

Exclusion Criteria

• patient with prior surgery of knee or foot . -secondary osteoarthritis. -valgus knee.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
: Radiological changes in hindfoot and midfoot alignment after correction of varus knee by High tibial osteotomy (HTO) or total knee arthroplasty(TKA)	6-12 months	This study evaluated the change in foot alignment after TKA or HTO by: 1. prospectively analyzing the correlation between the knee joint and the foot deformity.; 2. post-operative improvement in the foot deformity.; 3. the long-term post-operative changes in foot alignment.

Secondary Outcome Measures

Name	Time	Method
clinical assessment of the foot by american orthopedic foot&ankle society ( AOFAS) before and after knee correction	6-12 months	AOFAS covers four different regions of the foot: The ankle-hindfoot, midfoot, metatarsophalangeal (MTP)-interphalangeal (IP) for the hallux, and MTP-IP for the lesser toes.These four anatomic regions have their own version of the AOFAS survey. Each c is designed to be used independent of the others. However, each measure is comprised of nine questions and cover three categories: Pain (40 points), function (50 points) and alignment (10 points). These are all scored together for a total of 100 points