NCT00870025已完成4 期
hCG Priming Prior to COH in Poor Responder IVF Patients
IVI Madrid2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2008年10月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- pregnancy rate
研究概览
简要总结
There is a decline in androgen concentration with ovarian aging. Also, ovarian response to COH in IVF cycles diminishes with ovarian aging. Recent evidence suggest that testosterone or DHEA may improve ovarian response in poor prognosis patients by increasing intraovarian androgen concentration. A physiological way to induce androgen synthesis within the ovary is to stimulate theca cells androgen production by hCG stimulation. By doing this in the previous cycle we might expect a better response to COH.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 41 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •previous IVF cycle with 5 or less mature follicles or 5 or less oocyte retrieved
排除标准
- •42 years or older
- •BMI <18 or >30
结局指标
主要结局
pregnancy rate
时间窗: 2 weeks after intervention
次要结局
- number of oocytes retrieved(2 weeks after intervention)
研究者
研究点 (2)
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